产品描述:Rabbit polyclonal antibody to GSK3 alpha/beta (Phospho-Y279/216)免疫原:KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y279/216 of human GSK3 alpha/beta protein. The exact sequence is proprietary.纯化方式:The antibody was purified by immunogen affinity chromatography.克隆类型:Polyclonal产品形式:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.稀释比:WB (1/500 - 1/1000), IH (1/100 - 1/200)基因名称:GSK3A; GSK3B相关名称:GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
基因编号(人):
2931;
基因编号(小鼠):
606496;
56637;
基因编号(大鼠):
50686;
84027;
蛋白编号(人):
P49840;
P49841;
蛋白编号(小鼠):
Q2NL51;
Q9WV60;
蛋白编号(大鼠):
P18265;
P18266;
储存效期:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of GSK3 alpha/beta (Phospho-Y279/216) expression in mouse testis (A), rat testis (B), rat spleen (C) whole cell lysates. (Predicted band size: 50; 46 kD; Observed band size: 51; 46 kD)
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Immunohistochemical analysis of GSK3 alpha/beta (Phospho-Y279/216) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Inhibition of glycogen synthase kinase 3beta (GSK3beta) decreases inflammatory responses in brain endothelial cells
Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells
Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B
Distinct expression and activity of GSK-3a and GSK-3ß in prostate cancer
Activity-dependent regulation of dendritic growth and maintenance by glycogen synthase kinase 3ß
CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation
Exogenous Activation of Wnt/ß-Catenin Signaling Attenuates Binge Alcohol-Induced Deficient Bone Fracture Healing
Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of ß-catenin
The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of ß-catenin through mechanisms involving FRAT1 and PAK4
Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer