产品描述：Peptide to [D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P产品形式：Lyophilized powder CAS编号：96736-12-8分子式：C79H109N19O12分子量：1516.87纯度：> 95%化学结构：D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2背景应用：[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P initially described as a low potency ghrelin receptor antagonist has surprisingly been found to be a full inverse agonist (EC₅₀ = 5.2 nM). In COS-7 cells transiently transfected with the ghrelin receptor the substance P analog rPKPfQwFwLL decreased the constitutive signaling down to levels observed in untransfected cells. Assuming that constitutive signaling of the ghrelin receptor is of physiological relevance in the regulation of appetite control, inverse agonists of the ghrelin receptor could be interesting for the treatment of obesity.储存效期：Shipped at 4°C. Store at -20°C for one year.

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