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CCP1576
产品名称:Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide
货号:CCP1576
来源:Synthetic
反应物种:
实验应用:
*反应物种注解:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
*实验应用注解:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
规格
价格(元)
1 mg
440
5 mg
1320
10 mg
2200
Ship in 3 weeks
产品描述:Peptide to Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide
产品形式:Lyophilized powder
CAS编号:339990-02-2
分子式:C35H46N6O8
分子量:678.79
纯度:> 95%
化学结构:Ac-Leu-Pro-Phe-Phe-Asp-NH2
背景应用:The pentapeptide Ac-LPFFD-NH2 (iAβ5p) is an analog of product [Pro18, Asp21]-Beta-Amyloid (17-21) with small chemical modifications which enhance its stability against proteolytic degradation. iAβ5p acts as a β-sheet breaker peptide and crosses the blood-brain barrier at a higher rate than most proteins and peptides known to be selectively taken up by the brain so that it is assumed that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer`s disease (AD) models is additionally reported for iAβ5p.
储存效期:Shipped at 4°C. Store at -20°C for one year.
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