产品描述:Peptide to Amylin, Rat产品形式:Lyophilized powder
分子式:C165H261N51O55S2分子量:3903.4纯度:> 95%化学结构:H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge Cys2-Cys7)背景应用:Endogenous peptide secreted by pancreatic β-cells. Potently activates amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptors. Potently inhibits insulin-stimulated glucose uptake (IC50 = 12 pM). Implicated in type II diabetes.储存效期:Shipped at 4°C. Store at -20°C for one year.